OPH researches, develops and produces medicines to treat psoriasis for patients to have a better quality of life.

Bangkok, – The Government Pharmaceutical Organization (GPO) researches, develops, and produces drugs to treat psoriasis. For patients to have a better quality of life Because it is a disease that cannot be completely cured You will need to take medication to support your symptoms for the rest of your life. The exact cause of the disease is still unknown.

From the statistics of the Department of Medical Services The Skin Disease Institute found that currently Thailand has psoriasis patients, approximately 2% of the total Thai population. which psoriasis is a chronic disease Patients need to see a doctor continuously. Because it is a disease that cannot be cured. But the symptoms can be controlled. by proper treatment For most patients, there are few symptoms. Can use external medicine or radiotherapy to specific lesions to control symptoms, and approximately 20-25% with severe symptoms require treatment with oral medications that suppress the immune system. artificial sunlight or biomolecule injections It must be closely supervised by a medical professional.

Dr. Mingkwan Suphanpong, Director of the Government Pharmaceutical Organization, said that psoriasis is classified as a chronic skin disease. The main symptom is a red, raised rash with clear boundaries and covered with thick, silvery flakes caused by skin cells dividing and increasing rapidly for no apparent reason. Some people have pustules. Spread throughout the body and scalp There are also abnormal nails. The rash may be itchy or may be accompanied by symptoms of arthritis deformity. In addition to psoriasis, there are also skin symptoms. It may also be found together with other diseases such as coronary artery disease, diabetes, high cholesterol, paralysis, etc. Psoriasis is considered an important public health problem in Thailand. Because it is a disease that cannot be completely cured You will need to take medication to support your symptoms for the rest of your life. The exact cause of the disease is still unknown. Current evidence indicates that it is likely caused by a combination of factors, including genetics, the immune system, and external triggers. There are 4 main methods for treating psoriasis: 1. External medication such as steroid medication. Vitamin D topical Tar topical and Dithranol (Anthralin) topical 2. Oral medications such as Methotrexate Retinoid and Cyclosporine 3. Ultraviolet light irradiation such as Narrowband UVB and PUVA and 4. Biomolecule injections such as Etanercept, Infliximab and Ustekinumab. This is because psoriasis is a chronic disease whose cause is still unknown. And currently there is no cure for the rash. Therefore, you should consider choosing a treatment that controls the rash well. and has minimal side effects

Dr. Mingkwan further said that the Government Pharmaceutical Organization has researched, developed and produced medicines for treating and relieving symptoms for patients with psoriasis, including steroid creams. These include Mometasone furoate 0.1% cream, Triamcinolone acetonide 0.1% cream, Betamethasone valerate 0.1% cream, and Triamcinolone acetonide lotion 0.02%. There is also a medicine that is currently being registered, including Hydrocortisone acetate 1% cream, which It is a collaboration between the Government Pharmaceutical Organization and the Institute of Skin Diseases.

For tar drugs It is a product that contains important substances: Coal tar or coal tar, which is crude oil obtained from the distillation and destruction of coal at high temperatures. Currently, the Government Pharmaceutical Organization has two tar medicinal products: Coal tar topical solution cream 5% and Coal tar topical solution shampoo 20%, which are classified as effective medicines in treating psoriasis. But the side effects are low. And it is a drug that the Skin Disease Institute has produced for use in the treatment of psoriasis for more than 40 years. The Skin Disease Institute has a demand for Coal tar topical solution cream 5% and Coal tar topical solution shampoo 20%. in large quantities, but production capacity is limited This makes the distribution of medicines from the Skin Disease Institute to various hospitals difficult, thus causing problems in accessing medicines for patients in need. Therefore, the Skin Disease Institute has cooperated in researching and developing Coal tar topical solution cream 5% and Coal tar topical solution shampoo 20% with the Government Pharmaceutical Organization. By controlling drug production according to GMP principles and controlling drug quality according to the pharmacopoeia requirements. In order to make the medicine effective and safe for patients, in addition, from the concept of tar as a drug that helps treat psoriasis. The Government Pharmaceutical Organization has changed the appearance of the product to make it different from the original drug form. With pictures of various types of coral. which when deposited will become tar To help heal the patient's mental state when using the product. It is expected to be able to enter the market in December 2023.

Director of the Government Pharmaceutical Organization Added that Psoriasis patients It can be found in children, working people, and elderly patients. Of these, most patients had only mild symptoms. appropriate treatment It is the application of topical medicine to the skin. or irradiation of specific lesions For patients with more severe symptoms, they need to be treated with oral medications that suppress the immune system. artificial sunlight which can use health insurance rights throughout the country Social security rights and civil servant rights However, there are some patients who do not respond to the above treatments and need to be treated with biomolecule injections, which are highly effective and safe, but are expensive and cannot be reimbursed. The patient must pay for it himself. causing problems in accessing medicine Although there is no cure for psoriasis, there is no cure for psoriasis. But current treatments can reduce the rash and calm the symptoms. Patients can return to normal daily life like normal people. The patient still has to apply medicine from time to time. or take medicine Under the supervision of a doctor It's like treating general diseases. Patients should change their behavior and take care of themselves. Get enough sleep. Eliminate stress Exercise regularly Eat nutritious food You should not allow yourself to be overweight as this will affect your treatment. In addition, patients need to avoid stimulating factors that cause rashes, such as scratching, drinking alcohol, and most importantly, they should always maintain good health. -Thai news agency

Source: Thai News Agency

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